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Nerves that transmit signals from the brain are called motor or efferent nerves, while those nerves that transmit information from the body to the CNS are called sensory or afferent.

Most nerves serve both functions and are called mixed nerves.

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Nerves are large enough to have been recognized by the ancient Egyptians, Greeks, and Romans, but their internal structure was not understood until it became possible to examine them using a microscope.

"It is difficult to believe that until approximately year 1900 it was not known that neurons are the basic units of the brain (Santiago Ram? Equally surprising is the fact that the concept of chemical transmission in the brain was not known until around 1930 (Henry Hallett Dale) and (Otto Loewi).

There are, however, a few exceptions to this rule, notably including the part of the forebrain called the basal ganglia Arthropods, such as insects and crustaceans, have a nervous system made up of a series of ganglia, connected by a ventral nerve cord made up of two parallel connectives running along the length of the belly.

The sympathetic nervous system is activated in cases of emergencies to mobilize energy, while the parasympathetic nervous system is activated when organisms are in a relaxed state.

Grey matter is found in clusters of neurons in the brain and spinal cord, and in cortical layers that line their surfaces.

There is an anatomical convention that a cluster of neurons in the brain or spinal cord is called a nucleus, whereas a cluster of neurons in the periphery is called a ganglion.

The vertebrate nervous system can also be divided into areas called grey matter ("gray matter" in American spelling) and white matter.

Grey matter (which is only grey in preserved tissue, and is better described as pink or light brown in living tissue) contains a high proportion of cell bodies of neurons.

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